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CBDV: The Cannabinoid That Combats Seizure Activity

Studies have revealed the sometimes striking effectiveness of CBDV in the effort to help those who suffer seizure activity.

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CBDV
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The cannabis herb produces 113 special medicinal molecules called cannabinoids that have been found to improve human health. Commonalities in the efficacy of these chemicals quickly become apparent. The major health benefits of cannabinoids include a reduction of system inflammation, the ability to reduce or eliminate cancerous tumors, analgesic (painkilling) qualities, and a reduction of anxiety. Of these cannabinoids, cannabidivarin (CBDV) stands out for its ability to help those who suffer from conditions such as epilepsy, Crohn’s disease, and multiple sclerosis.

This non-psychoactive cannabinoid is most common in landrace indica strains and typically present in greater quantities in plants that are low in tetrahydrocannabinol (THC) and rich in cannabidiol (CBD).

Cannabis strains that have shown to be relatively rich in CBDV include Dance World, Euphoria, Harlequin (also known for being rich in CBD), Painkiller XL, Royal Medic, and Shark Shock.

The Details of CBDV

Research has revealed that possibly the greatest benefit offered by the CBDV cannabinoid is to those who suffer diseases and conditions related to seizures, such as epilepsy and Dravet Syndrome (epilepsy alone affects 50 million people globally). When combined with cannabinoids like THC and THCV, which have also been found to deliver sometimes stunning efficacy for epilepsy patients, CBDV is a powerful option. This is especially true for patients with intractable conditions for which conventional pharmaceutical therapies are ineffective.

A research study conducted in 2014 entitled “Nonpsychotropic Plant Cannabinoids, Cannabidivarin (CBDV) and Cannabidiol (CBD): Potential for the Treatment of Neuronal Hyperexcitability” and published in the journal ACS Chemical Neuroscience found that CBDV “reduced both epileptiform burst amplitude and duration” in epilepsy patients. Interestingly, the study revealed that capsaicin, an active ingredient of chili peppers, also contributed to a reduction in seizure activity, including severity and length of episode.

The Research

A variety of research studies have revealed the sometimes striking effectiveness of cannabinoids such as THC, THCV, CBD, and CBDV in the effort to help those who suffer seizure activity and diseases such as epilepsy and Dravet Syndrome.

A 2012 study entitled “Cannabidivarin is Anticonvulsant in Mouse and Rat” and published in the British Journal of Pharmacology found CBDV to be a powerful anticonvulsant for a variety of diseases and conditions.

Concluded the study’s researchers, “These results indicate that CBDV is an effective anticonvulsant in a broad range of seizure models. Also, it did not significantly affect normal motor function and, therefore, merits further investigation as a novel anti-epileptic.”

Another study conducted in 2012 concluded that CBDV can sometimes dramatically reduce the gastrointestinal inflammation that characterizes many common diseases, including Crohn’s disease, inflammatory bowel disease, and irritable bowel syndrome. Entitled “Cannabinoid Actions at TRPV Channels: Their Potential Relevance to Gastrointestinal Inflammation” and published in the Oxford journal Acta Physiologica, the study concluded, “Cannabinoids can affect both the activity and the expression of TRPV1-4 channels, with various potential therapeutic applications, including in the gastrointestinal tract.”

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Cannabis Classification System Announced for 2022 Emerald Cup Awards

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Cannabis Classification System

One of the factors that make the Emerald Cup so important to California’s cannabis market is its continued strive for excellence and innovation. For the 2022 awards, the judging process is undergoing a transformation and with it comes a new cannabis classification system that will classify entries based on terpenes, flavour, and effects for anybody — from customers to budtenders, dispensaries, judges, and cultivators.

Cannabis Is More Than Just THC

The days of just searching out the highest THC totals are rapidly receding as research has now proven that terpenes are at the base of the entourage effect that customers desire are rapidly fading.

Terpenes, on the other hand, have mostly added to the consumer confusion already caused by overly broad Indica/Sativa/Hybrid terminology, whimsical strain names, irrelevant THC/CBD percentages, and other ambiguous factors that make selecting the best or correct strain a less-than-satisfying ordeal for even the most experienced cannabis connoisseurs.

The Emerald Cup competition will serve as a testbed for a new classification system for cannabis flowers. The event organisers and their testing partners at SC Labs decided to further break down the flower categories based on the chemometrics of each cultivar (better known as “chemovar” — the evolution of the term “dominant terpene”) evolving beyond last year’s flower category sorting by primary terpene content, in order to level the playing field and eliminate as much bias as possible in the blind/anonymous sampling done by Emerald Cup judges each year.

This paradigm-shifting insight sparked months of additional research and discussion, culminating in the Emerald Cup Cannabis Classification System based on PhytoFacts® powered by SC Labs.

The all-new classification system builds on last year’s approach of sorting flower entries by primary terpene content, leveraging a decade of Cannabis phytochemistry research between PhytoFacts®, developed by Napro Research in 2013, and a powerful database of over 250,000 terpene tests aggregated by SC Labs, dating back to their launch of terpene testing on Cannabis in 2013. The key class names were chosen to represent current terminology, are widely used in the business and are familiar to dispensaries and consumers. Each class is further explained using taste notes, effects, and popular strains or cultivars to promote understanding and acceptance.

The New Cannabis Classification System

The classes of the Emerald Cup Cannabis Classification Based on PhytoFacts® powered by SC Labs include:

“Jacks + Haze” Class

  • Mostly ‘Sativa’-leaning varietals
  • Tasting notes – Fruity, Pinesol, Haze
  • Effects – Energizing, Cerebral, Artistically Inspiring
  • Common Cultivars – Classic Trainwreck, Jack Herer, Durban Poison, Super Lemon Haze
  • Terpenes Profile: Terpinolene, Caryophyllene, Myrcene

“Tropical + Floral” Class

  • Mostly ‘Indica’-leaning varietals
  • Tasting notes – Sweet, Floral, Tropical Fruit
  • Effects – Calming, Soothing, Relaxing
  • Common Cultivars – Super Skunk, Hawaiian, In the Pines, Dream Queen
  • Terpenes Profile: Ocimene, Myrcene

“Sweets + Dreams” Class

  • Mostly ‘Indica’-leaning varietals
  • Tasting Notes – Fruity, Sweet, Woody, Hoppy, Herbaceous
  • Effects – Relaxation, Couch Lock, Analgesic
  • Common Cultivars – Blue Dream, Tangie, Forbidden fruit, Grandaddy Purple, Purple Urkel, Grape Ape, Cherry AK, God’s Gift, Purple Punch
  • Terpenes Profile: Myrcene, Pinene, Caryophyllene

“OGs + Gas” Class

  • True ‘Hybrid’ varietals
  • Tasting Notes – Gas, Fuel, Sweet, Citrus, and Pepper
  • Effect – Uplifting, Stimulating, Analgesic, Relaxation
  • Common Cultivars – Classic OG Kush, ChemDawg, Sour Diesel, Gorilla Glue
  • Terpenes Profile: Any combination or shifting codominance of Caryophyllene, Limonene, Myrcene

‘”Desserts” Class

  • True ‘Hybrid’ varietals
  • Tasting Notes – Deserts, Doughs, Citrusy & Spicy
  • Effects – Stimulating, Racy, Uplifting, Comforting
  • Common Cultivars – Classic Bubba Kush, GSC, Gelatos, Cakes
  • Any shift in codominance of Caryophyllene & Limonene

“Exotics” (Rare Terpene Combinations) Class

  • True ‘Hybrid’ varietals
  • Tasting notes – varied based on chemistry of entry
  • Effect – varied based on chemistry of entry
  • Common Cultivars – rarest terpene profiles entered into the Emerald Cup Competition

This game-changing development in cannabis classification levels the playing ground for the 2022 Cup as well as market competitiveness amongst brands. The system seeks to become an open-source, globally recognised grading solution for Cannabis, with six simple classes/names/descriptions. In the same way that a Chardonnay would not be tested against a Merlot in the wine business, this new system permits strains with comparable profiles to be judged against each other. This new classification system will also be used at the California State Fair Cannabis Awards in July 2022.

The 2022 Emerald Cup Awards will be presented live on stage on May 14th at the Green Street Festival in Downtown Los Angeles, California.

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The Sativa Preservation Society Project Will Protect Rare Haze Genetics

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Sativa Preservation Society Project
PHOTO | SATIVA PRESERVATION SOCIETY PROJECT

Space Coyote, the totally cosmic cannabis company, has launched the Sativa Preservation Society Project — a movement that protects Haze genetics while paying homage to the custodians and cultivators who kept the seeds alive.

Celebrators of the cannabis culture’s stoner heritage, Space Coyote’s aesthetic and ethos embraces the vibes and psychedelic Seventies scene, where the creativity and community of cannabis intersect.

Co-founder and self-confessed ‘Sativa Diva’ Libby Cooper calls it the “ultimate passion project”. 

“We’re truly passionate about saving these genetics that are the actual grandmothers of every modern-day sativa strains that people love — all of these desert strains, all of the fruity strains,” Cooper tells me from the Space Coyote van en route to Hall of Flowers.

Founding the Sativa Preservation Society Project

The concept of the Sativa Preservation Society Project was years in incubation as the Space Coyote team deliberated over how to bring it to life. It was important for them to give back to the community while helping to educate about the history of cannabis culture.

The stars aligned earlier this year when the team met Bam Vachher-Gnanathurai, nursery and plant breeding manager from the Posibl Project in Salina. A mutual love of the unique effects of Haze genetics made for a truly cosmic outcome.

“Bam is super passionate about sativa,” said Cooper. “When we went and met up with Bam for the very first time, he rolled a blunt from Cuban Black. It was such an amazing experience to smoke that flower.” 

“The initial conversation of the Sativa Preservation Society coming to life happened during that smoke session. It was like, ‘holy shit, we could actually do this.’”

The Haze Experience

The Sativa Preservation Society Project is launching with three incredibly rare cultivars — Cuban Black Haze, Uptown Haze (also known as A5 Haze), and C5 Haze — all of which were originally cultivated in the 1980s by legendary grower Neville Schoenmaker. The flower will be available as bagged eighths and as infused prerolls.

Cooper likens the Haze experience to being “a bit like mushrooms” — colors are brighter, your smell is enhanced and your hearing is sharper.

“It’s really like a cup of coffee without any jitteriness or anxiety usually associated with sativas. This is pure energy without any sort of adverse effects,” explains Cooper. “You really feel as if your eyelids are getting peeled back — you’re awake, you’re uplifted. Basically, I smoke it and I immediately start stretching.”

“Many sativa genetics are dying out due to a number of reasons,” says Cooper. “Typically, they are more difficult to grow, have a longer curing time, and the fluffy buds are easily crushed in transit.” All of which makes sativas less cost-effective in California’s highly competitive legal market.

“This truly is the first time these original sativa strains are going to be commercially grown,” says Cooper. “It really wouldn’t have been possible, funnily enough, without this group named Posibl.”

Learn more about the Sativa Preservation Society Project in the video above. While you’re at it, find your nearest Space Coyote here.

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Peach Oz: This Sweet And Juicy Cultivar Will Stimulate Your Creativity

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PEACH FUZZ | PHOTO: WONDERBRETT

If you’re looking for a premium cultivar with legendary genetics and a euphoric high, look no further than Peach Oz, the latest addition to Wonderbrett’s stellar strain menu.

A cross of Peach Rings with OZ Kush and a descendent of Zkittlez, the sweet, stimulating citrus taste profile of Peach Oz will get your creative juices flowing.

While the cultivar may be new to the public, according to Wonderbrett Co-Founder and famed Breeder Brett Feldman, it’s five-years-old in the world of genetics.

“There’s only a small handful of heady smokers who follow these things,” says Feldman. “I wanted to bring it to the masses to share the experience with everybody. That’s where my passion comes from with this strain. Similar to an amazing dish at a restaurant, you want to share it with your friends.”

Grown in small-batches at scale from the company’s state-of-the-art Long Beach cultivation facility, the strain was first created by Dying Breed Seeds, then perfected by Cannabis By Corey, before making its way to Feldman.

Wonderbrett’s grow room | PHOTO: Courtesy Wonderbrett

Bursting with flavors and aromas that bring to mind the sweet ocean breeze and fragrant fruit orchards of the California sunshine state, Peach OZ’s four dominant terpenes: Caryophyllene, Linalool, Limonene and Humulene, create a distinct sweet taste of ripe peaches, citrus candy and cream.  

“When any strain has that unique, recognizable consistency in its flavor, whether that be peach, lemon or orange, that’s what myself and other breeders appreciate most and look for when bringing a genetic like this to market. It’s mind-blowing what Peach OZ can do that, translating a fruit flavor to a smoking experience,” explained Feldman.

Peach OZ is available at select dispensary and at Wonderbrett’s flagship dispensary in L.A.

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