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The Emerging Science of Psychedelic Therapies for Our Wellbeing

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Psychedelic Therapies
PHOTO | Martina
Dr.Dabber SWITCH Clear Edition

This month, the city of Dever Colorado made the landmark decision to decriminalize psilocybin mushrooms. It’s the first U.S. city to do so. More famously known as “magic mushrooms” these intoxicating yet non-addictive fungi grow naturally throughout most of the United States. And yet, psilocybin and psilocin have been illegal in the country since 1969, when the use of psychedelic drugs became widespread in consumer culture.

In Denver, the initiative to decriminalize passed with a narrow margin—50.6 percent of voters approved the bill. Dubbed Initiative 301, the bill makes the personal possession of magic mushrooms among those 21 and older one of the lowest law enforcement priorities. The bill also prevents city authorities from spending money on resources dedicated to prosecuting or pursuing criminal charges against adults who possess or consume the mushrooms.

The recent change not only makes Denver the most psychedelic-friendly city in the United States, but it also represents a major shift in cultural, political, and even medicinal views on mind-altering plants and other natural products. Westerners have found themselves amidst a revived psychedelic therapies renaissance, a renaissance supported by a new wave of scientific research.

A New Psychedelic Renaissance (Yet Again)

This unique time period in Western culture has recently been dubbed the second psychedelic renaissance. All jokes comparing modern-day millennials and free-loving hippies aside, the “second psychedelic renaissance” is, in reality, far from the second. Back in the 1960s and 70s, psychedelics were first introduced to a consumer-focused capitalist culture. Yet, the use of mind-altering plants and periods of intense social drug consumption have dotted history books for generations.

Take, for example, the mid-1800s when European elites had their first taste of hashish. The habit was originally picked up by French soldiers in Egypt, who brought the compressed cannabis resin home with them after the French invasions led by Napoleon Bonaparte. The almost hallucinogenic experiences the hashish provided lead to a slight cultural obsession with hallucinogens among those who could afford the substances, and novelists like the great popularized the hallucinogenic experience through their writings.

As early as 1729, Chinese Emperor Yung Chen issued the first rulings criminalizing the recreational use of opium. While opium is not a hallucinogen, a growing culture of recreational drug use and addiction originally propagated by Portuguese imports of the plant into China inspired Chinese leadership to continue to crack down on opium trade over the next three centuries. It is important to mention, however, that unlike psychedelic drugs, narcotics such as opium come with a high risk of addiction.

These are simply examples from the last three hundred years. And yet, if archeological evidence is any indication, human civilizations across the globe have always had some sort of relationship with psychoactive substances — just recently, archeological researchers in Bolivia found evidence of a 1,000-year-old pouch that contained traces of five different psychoactive plants.

The tradition of medical cannabis consumption in China is thought to date as far back as 2,737 BC when mystical Emporer Shen-Neng is believed to have introduced cannabis and many other plants into medical practice. Shen-Neng is believed to be the father of traditional Chinese medicine, although the medicinal uses of cannabis in China were not recorded until the first or second century A.D.

More recently, however, this old tradition has been reintroduced to Western scientific practice. After medical researchers took a brief hiatus from psychedelic research during the late 70s, through the early 90s, psychiatrists and other medical professionals are once again exploring the opportunities of these unusual and transformative therapies.

For the city of Denver, greater tolerance for psilocybin may provide the first of many long steps toward decreasing barriers for researchers and other psychedelic proponents who hope to develop the medical and spiritual legitimacy of the psychoactive experience.

The Vast Potential of Psychedelic Therapies

The most profound implications of psychedelic medicine lie in the arena of mental health. In 2016, the first magnetic resonance imaging (MRI) scans provided glimpses into the brain on LSD. Colloquially known as “acid”, LSD is considered a classical psychedelic capable of radically altering cognition and cultivating feelings of harmony and oneness with the universe.

When put under the MRI machine, the brains of those on LSD did something magnificent — they lit up, nearly all the way up. Normally, when the human brain processes visual imagery, very specific regions of the brain activate. These regions are the visual cortex and the visual association areas that normally process information taken in by the eyes.

After an injection of LSD, however, brain scans revealed that networks across the entire organ were activated, linking portions of the brain that do not typically fire together. The psychoactive truly inspired a whole-brain experience. According to the leading scientists on the experiment, those that were given LSD were “seeing with their eyes shut.”

Brain scans of the effects of psilocybin extracted from mushrooms have made similar findings. In 2014, research published in the Journal of the Royal Society Interface used functional magnetic resonance imaging (FMRI) to map the effects of the psychoactive substance on communication pathways between various processing networks in the brain.

Similar to the LSD study, the brains of patients given psilocybin were extra-active. The psychotropic compound caused a marked increase in connections between various networks, transforming normal pathways into a super-highway system with dense web-like construction.

Psychedelics, it would seem, encourage a unique explosion of brain activity that links up previously remote pockets of the mind. This mind-melting may have long-lasting positive effects to boot—research suggests that the “mystical-type” experiences inspired by psilocybin provided some of the most meaningful moments of spiritual significance in the lives of study participants.

Depression

Some of the most groundbreaking research in psychedelic therapies are occurring in the arena of depression. A handful of trials have examined the potential of psychotropic therapies in depression in patients with life-threatening illnesses, yet hallucinogenic therapies may be useful in treatment-resistant depression as well.

In 2017, for example, researchers from Imperial College London found that psilocybin seemed to press the brain “reset” button in patients with clinical depression. The study found that after taking the psychedelic, activation of brain regions responsible for fear and anxiety became less active. Further, the brain’s “default mode”, so to speak, became more stable after treatment.

Obsessive Compulsive Disorder

Back in 2006, a study published in the Journal of Clinical Psychiatry found that psilocybin was effective in reducing the acute symptoms of obsessive-compulsive disorder. The study, however, only included nine total participants. More recently, however, a clinical trial of psilocybin for OCD is underway at Yale University and the Heffter Research Institute. The trial contains 30 active participants, although the final results will not be published until 2022.

Addiction

Research from 2014 and 2015 tested the effects of psilocybin therapies in patients suffering from tobacco and alcohol addiction. The studies, which were conducted as proof-of-concept trials, found that treatment with the psychoactive compound decreased cravings for alcohol and nicotine for several months after administration. Alcohol cravings were reduced for up to 36 weeks after a psilocybin treatment. Tobacco cravings were also significantly diminished after six months of treatment.

End-of-Life Psychological Distress and Anxiety

Several human studies on psilocybin have been conducted in patients with depression and anxiety associated with life-threatening cancer diagnoses. In one 2016 study published in the Journal of Psychopharmacology, psilocybin inspired positive changes in mood, depression, and anxiety levels in cancer patients six months after treatment with the psychoactive. An improved mood, however, wasn’t the only benefit reported by the patients. 80 percent of study participants also reported improvements in quality of life, spiritual satisfaction, and improved life meaning.

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Sex & Sinsemilla: The Pleasure Enthusiast on Using Cannabis to Reduce Pain During Sex

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reduce pain during sex
PHOTO: amixstudio

For many a cannathusiast, sex and weed make the best of bedfellows. From helping you unwind and taking you out of your head, to increased sensation and pleasure, for some, the herb can be a natural aphrodisiac. An entire sub-category of cannabis products has been developed to help people enjoy sex more, whether it be to reduce pain during sex or to increase their connection with their partner.

Of course, cannabis and sex aren’t a great combination for everyone. There have been reports of the herb contributing to erectile dysfunction and premature ejaculation.

However, there is also research that suggests smoking herb increases orgasm length, raises sperm count, that cannabis improves their experience and people who partake in weed also partake in sex more frequently.

Enough sexy data talk. Valentine’s Day seemed like the right time to debut the sex and sinsemilla advice column from Cara Cordoni, Cannabis Aficionado’s resident Pleasure Enthusiast, who will be answering your questions around cannabis, intimacy and sex, as well as offering up product reviews and suggestions to help you maximize your sexy times.

Dear Pleasure Enthusiast,

I want to have a sexy night with my partner, but I’ve been experiencing pain during penetration. I’ve heard that cannabis can help… can it?

– Sexy ‘n Suffering

Dear Sexy ‘n Suffering,

You’re not alone in experiencing pain during sex — and the first order of concern is to explore the root cause. Has there been an injury? Are you emotionally comfortable and safe? Is there an underlying condition like an infection, endometriosis or fibroids? Have you been to see a medical professional? Understand the source before addressing the symptoms. Once you know what’s up, then yes, cannabis could help reduce pain during sex.

Many of us gals feel pain due to lack of lubrication, which can be addressed with relaxation, foreplay and the use of a sexual lubricant like Intimate Oil by Privvy Peach, Smooth Operator by Quim, Awaken by Foria or Quiver by HerbaBuena.

These lubes combine cannabis, in the form THC, CBD, or both and known herbal aphrodisiacs like passionflower extract to provide pelvic relaxation, increase blood flow and reduce inflammation. Many women experience enhanced sensitivity with these infused lubricants, as well. Quim is aloe vera based and safe with latex, while Foria is coconut oil-based and not latex friendly. Luckily, there are many options on the market in legal states, or with CBD for everyone. I always recommend a patch test before applying to your privates. And if the first one you try doesn’t suit you, don’t give up, try another as each is unique.

I applaud you on your journey of pain reduction and pleasure enhancement.

The Pleasure Enthusiast at Work

QUIM: Smooth Operator

Squirt squirt; a slippery, opaque, white liquid coats on my fingers. Smooth Operator reminds me vaguely of semen, which is both titillating and disturbing. I apply it liberally to myself for a solo test flight. I wait for the 5-7 recommended minutes for the serum to penetrate and take effect feeling hopeful and skeptical. Yet as I read Quim’s elegant pamphlet, the slippery serum feels fantastic on my clit and labia and I notice that blood flow is visibly increased. Everything is gently engorging and I like it.

Foria: Intimacy CBD Lubricant and Awaken

I apply four squirts of Awaken directly to my vulva. I like the smell: it’s faint, the slightest edge of thin mint. The feeling is almost immediate, a coolness, very subtle and engaging, then a warmth. I see and feel blood flow increasing.

I then pour Foria’s clear coconut oil-based lube into my palm — it’s messy, some runs down the bottle. Coconut oil is my preferred lubricant when there’s no latex involved, so this liquid oil feels nice. After some experimentation, I find Foria’s products are super helpful with anal play, where the relaxing and slightly numbing qualities work best.

Do you have a question about sex that you’d like the Pleasure Enthusiast to answer? Get in touch: contact@cannabisaficionado.com.

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New G Pen & B Real Collab Seamlessly Fuses the Best of Cannabis Culture

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B Real
PHOTOS | Grenco Science

In these days of uncertainty and social distancing, it’s refreshing to finally see some good news. Two pioneers of cannabis culture, Grenco Science (G Pen) and Cypress Hill frontman B Real have joined forces to launch a range of co-branded products.

“We’ve had a longstanding relationship, and to partner with B Real in an official capacity now is an honor,” said Chris Folkerts, CEO and Founder of Grenco Science in a press release.

“B Real has been a cultural force in both music and cannabis, and together with Grenco Science, we are reinventing the cannabis experience for our customers who have come to expect quality and innovation like only Grenco Science can provide.”

Grenco Science’s new partnership with the critically acclaimed artist and entrepreneur behind Dr. Greenthumb’s Dispensaries will see a line of products introduced to the market, that is set to include co-branded product offerings and fully integrating the G Pen line into Dr. Greenthumb’s Dispensaries with custom build-outs in California.

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Cannabis Aficionado’s Guide to a Luxurious Valentine’s Day

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Luxurious Valentine's Day
PHOTO | Maria Valentino in her luxury cannabis-inspired fine jewelry.

Treat yourself or that special someone with the Cannabis Aficionado guide to partaking in a luxurious Valentine’s Day. From precious jewels to pleasuring lubes, silky robes to stylish home decor, the dankest weed to delicious chocolate treats, there’s something for all you lovers out there.

1906

Luxurious Valentine’s Day

Lovers Edition

Lovers Edition combines five herbal aphrodisiacs with cannabis to create what they call “the best sex drug in the world.” It’s formulated for both a physical and psychological high, working to increase blood flow while also helping you relax and get out of your head.

Foria

Awaken

This multi-aphrodisiac blend is formulated for people with vulvas, to enhance tactile sensation and pleasure while decreasing tension, discomfort and dryness.

Genifer

14kt Yellow Gold Sativa Marijuana Leaf Diamond Pavé Pendant

Genifer Murray and Glenn Murray are expert jewelry makers as well as being passionate cannabis advocates. This beautiful sativa leaf pendant necklace is artfully crafted from 14kt gold and is available in a variety of sizes.

Jacquie Aische

Luxurious Valentine’s Day

1 Diamond Pave 3 Sweet Leaf Dream Catcher Hoops

Jacquie Aische designs jewelry with the intention of empowering women. Join her tribe with these stunning Dream Catcher Hoops from her Sweet Leaf collection.

Jonathan Adler

Botanist Ganja Urn

The Ganja Urn from Jonathan Adler’s Botanist collection is the perfect bougie scene-stealer — a must-have for all cannabis aficionado’s to stash their secrets.

Maria Valentino

Cannabis Leaf Diamond Ring

Maria Valentino is a cutting-edge formulator and leader of green beauty and wellness for conscious consumers. This statement ring from her fine jewelry collection features pave diamonds, emulating the plant’s natural trichomes, and is set in 14k gold.

House of Saka

Sparkling Pink

Toast to love with House ofSaka’s luxurious sparkling pink wine. Based on grapes from Napa Valley’s terroir and infused with the finest craft harvest. The resulting experience is intended to leave the imbiber feeling invigorating, clean and relaxed.

Satori

Luxurious Valentine’s Day

Choc coated Strawberries

Sherbinskis

Pink Panties

Mario Guzman aka Mr. Sherbinski grows some of the finest cannabis you’ll ever experience. His Pink Panties cultivar is a cross of Burmese Kush and a Florida Kush backcross. It expresses dense, medium-sized buds that reek of tart and tangy citrus alongside a strong floral bouquet.

White Fox

White Fox on this planet is to formulate, alchemize and create specific effect driven medicine with the intention of showing you your own true greatness. Using a 2,000-year-old ayurvedic formulation, they have developed vape pens to increase your sexual energy and sensitivity.

Untamed is for women, to guide you to your greatest sexual expression and unbridled passion. Legendary for men will provide strength, vitality and legendary sexual performance.

Vintage Redeux

Luxurious Valentine’s Day

Cherry Mary Jane Smoking Robe

Vintage Redeux creates sinsemilla-inspired streetwear. Smoke, chill and bring sexy back to smoking in this beautiful satin smoking robe with a sultry hand sewn Mary Jane patch.

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